Alexandre Bonvin bio photo

Computational Structural Biology group focusing on dissecting, understanding and predicting biomolecular interactions at the molecular level.

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High Ambiguity Driven biomolecular DOCKing

based on biochemical and/or biophysical information.

Structure + Binformatic/Biophysical Data => Complex

Version: 2.4 (March 2024) (changes)

Authors: Alexandre Bonvin and members of the computational structural biology group, Utrecht University


Bijvoet Center for Biomolecular Research
Padualaan 8, 3584 CH Utrecht, the Netherlands
Phone: +31-30-2533859 Fax: +31-30-2537623

HADDOCK is one of the flagship software in the EU H2020 BioExcel Center of Excellence for Biomolecular Research

HADDOCK2.4 manual:

HADDOCK2.4 webserver:

Getting the software: license form

Questions about HADDOCK or looking for support? Ask BioExcel

HADDOCK best practice guide - A must read when starting to use our software!

An introduction to HADDOCK2.4: View the SBGrid [webinar]:

    View recorded lecture

( (June 29th, 2021).

Two lectures about integrative modelling and HADDOCK: Recording of a lecture by Prof. Bonvin at the 2021 BioExcel summerschool:

    View recorded lecture Part I (46 min.)

    View recorded lecture Part II (43 min.)


When using HADDOCK cite:

For additional citations when using specific modules see also our publication page.


HADDOCK is derived from ARIA scripts by Michael Nilges and Jens Linge.

The ongoing development of HADDOCK is the result of a team effort and in particular contributions from Cyril Dominguez, Aalt-Jan van Dijk, Sjoerd de Vries, Marc van Dijk, Ezgi Karaca, Panagiotis Kastritis, Adrien Melquiond, Mikael Trellet, Gydo van Zundert and Joao Rodrigues are acknowledged.

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Copyright © Hergé Moulinsart 2003