Alexandre Bonvin bio photo

Computational Structural Biology group focusing on dissecting, understanding and predicting biomolecular interactions at the molecular level.

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HADDOCK

HADDOCK

High Ambiguity Driven biomolecular DOCKing.

Structure + Binformatic/Biophysical Data => Complex

Version: 3.0 (first release May 2020)

Authors: Computational structural biology group, Utrecht University

Contact:

Bijvoet Center for Biomolecular Research
Padualaan 8, 3584 CH Utrecht, the Netherlands
Email: a.m.j.j.bonvin@uu.nl
Phone: +31-30-2533859 Fax: +31-30-2537623

HADDOCK is one of the flagship software in the EU H2020 BioExcel Center of Excellence for Biomolecular Research

ATTENTION: This new version is under heavy development and will change abruptly and without warning.


Description

HADDOCK v3.0 is a bottom-up reimagination of the long standing time-proven HADDOCK used for integrative modeling of biomolecular complexes. This young and still very experimental (use it at your own risk!) aims to modularize and extend HADDOCK’s core functions.

In its current implementation, HADDOCK v3.0 still lacks the full repertoire of features present at the production web server version, HADDOCK v2.4. However it is able to take full advantage of the ambiguous interaction restraints (AIRs) to drive the docking process.

It was evaluated using the Protein-Protein Docking Benchmark 5 and compared with the live version (v2.4). This evaluation was done using the true interface of each complex of (3.9 Å) and is expressed in terms of success rate; the amount of BM5 targets that have at least one docking solution below the specified threshold within a specified subset of solutions ranked by HADDOCK-score.

BM5


HADDOCK3 distribution download

HADDOCK v3.0 can be freely downloaded by completing the following form (see our privacy statement regarding the use of our portals):


... more than fish or software..., discover the "capitaine" ...

Haddock

Copyright © Hergé Moulinsart 2003